cervical dystonia patient hero

Is Cervical Dystonia Holding You Back?

XEOMIN May Help Provide Relief

What is Cervical Dystonia?

Cervical dystonia is a movement disorder causing involuntary muscle contractions in the neck that may twist and turn your head into uncomfortable positions. Symptoms may include painful muscle spasms, a tilted or rotated head, and the frustration of not being able to control your own movements.

Examples of abnormal postures

cd head tilting forward

Head tilts forward

cd head tilting back

Head tilts backwards

cd head rotates

Head rotates to left or
right side

cd head tilting to the side

Head tilts to the side

Images are for illustration purposes only. Individual results may vary.

* Cervical dystonia is the most common form of focal dystonia
* Estimated to affect more than 60,000 people in the United States in 20231

In clinical studies, XEOMIN was shown to reduce symptoms associated with adult cervical dystonia, including abnormal neck position and neck pain.

What is XEOMIN?

  • XEOMIN is an FDA-approved prescription medication that is used to treat adult cervical dystonia

  • XEOMIN is a botulinum toxin type A, which may help decrease muscle contractions and neck pain.2

  • XEOMIN is injected by your doctor

cd patient image for cool water background

My cervical dystonia became more painful to me, and obvious to others who pointed out that my head was tilted. It’s frustrating losing control of my own body.

45 year old

Not an actual patient.

How does XEOMIN work?

XEOMIN works by blocking the signals your nerves send to the muscles in your neck, so that these muscles can relax and not be as tight. This can improve your ability to move those muscles.
Patients typically start to see results one week after they start treatment with XEOMIN.
In clinical trials, most patients were retreated after 12 to 14 weeks.

Where is XEOMIN injected?

xeomin single bottle
Where is
XEOMIN
injected?

Your doctor will locate certain areas of the neck and shoulders and inject XEOMIN directly into those areas. If needed, retreatment with XEOMIN can occur every
12 weeks.

You and your doctor can decide the right plan for you.

Possible muscles involved

dystonian lateral v2 desktop

Markings show examples of muscles that may be treated for cervical dystonia in adults; however, not all possible injection locations are shown. Not all patients will receive treatment in the same muscle(s). Your doctor will determine the appropriate locations and doses for XEOMIN injection.

cervical dystonia sitting patient

Not an actual patient.

How can XEOMIN help you?

In clinical studies, XEOMIN was shown to reduce symptoms associated with adult cervical dystonia, including abnormal neck position and neck pain.

48%

(322/669)

of patients experienced a meaningful decrease in pain† after their first XEOMIN injection

†Greater than 30% pain reduction = meaningful decrease in pain.

10%

(69/669)

of patients experienced complete pain relief after their first treatment with XEOMIN§

§The analyses in this study were based on patients who had a baseline pain assessment and reported experiencing pain at baseline. Because several studies with different designs were combined for this analysis, it was not possible to compare pain responses of patients receiving XEOMIN with those patients receiving placebo or a different comparator drug in their first injection cycle. Individual results may vary.

The most common side effects in clinical trials of XEOMIN in adults
with cervical dystonia were:
Difficulty Swallowing|
Neck Pain|
Muscle Weakness
Pain at the Injection Site|
Muscle and Bone Pain

XEOMIN is manufactured with purity in mind.

xtract technology logo with r1
The active ingredient is purified by XTRACT Technology®, a state-of-the-art manufacturing process.

XEOMIN is uniquely purified to remove complexing proteins, leaving just the therapeutic component.
doctor administering XEOMIN on sitting patient

Move forward with XEOMIN, a uniquely purified option for cervical dystonia.

XEOMIN has been a trusted treatment for 7.7 million patients with various conditions from more than 70 countries. XEOMIN is a safe and effective treatment, which has been available in the U.S. for more than 14 years.

Not an actual patient. Individual results may vary.

Patient
Savings Program

Eligible commercially insured patients
Save up to $5,000 annually*
Start Saving Now 

Visit MERZCONNECT.com for additional information to help you
get started and stay on XEOMIN.

XEOMIN patient savings is
available in just 3 easy steps.

Restrictions apply to eligibility. Commercial insurance required.

Reimbursement limited to out-of-pocket XEOMIN medication costs and related administration fees. State limitations may apply. Please see Full Terms and Conditions at MERZCONNECT.com. Merz reserves the right to change XEOMIN Patient Savings Program Terms and Conditions, including the eligibility requirements, at any time. This is not health insurance.

You may be required to pay upfront for your co-pay/co-insurance, as determined by your insurance coverage/policy and your healthcare provider’s co-pay collection practice.

Once you and your doctor have decided XEOMIN is right for you, MERZ CONNECT offers you savings and support to help you get started and stay on therapy.

reclaim moments

Having challenges with cervical dystonia? There may be more you can do with XEOMIN.

If your current treatment is not meeting your expectations, talk to your doctor about XEOMIN today!

Talk to Your Doctor About XEOMIN Today 

Having challenges with cervical dystonia? There may be more you can do with XEOMIN

Talk to Your Doctor About XEOMIN Today 

Hear from real patients like you

Jan is an adult with cervical dystonia treated with XEOMIN. See her story.

Cervical Dystonia Jan Story

Patient Testimonials

Hear what real patients are saying about XEOMIN

Watch Now

Not actual patients. Individual results may vary.

Hear from real patients like you

Jan is an adult with cervical dystonia treated with XEOMIN

See Her Story

References

  1. National Organization for Rare Disorders. https://rarediseases.org/rare-diseases/cervical-dystonia/#affected. Accessed June 2024.
  2. XEOMIN® [Package insert]. Raleigh, NC: Merz Pharmaceuticals, LLC; 2023.
XEOMIN® (incobotulinumtoxinA)

XEOMIN may cause serious side effects that can be life threatening. Problems swallowing, speaking, or breathing can happen within hours to weeks after an injection of XEOMIN if the muscles that you use to breathe and swallow become weak. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with XEOMIN.

    • People with certain breathing problems may need to use muscles in their neck to help them breathe and may be at greater risk for serious breathing problems with XEOMIN.
    • Swallowing problems may last for several months, and during that time you may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN have the highest risk of getting these problems.
  • Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.

These symptoms can happen hours to weeks after you receive an injection of XEOMIN. These problems could make it unsafe for you to drive a car or do other dangerous activities.

What is XEOMIN?

XEOMIN is a prescription medicine:

  • That is injected into muscles and used to improve the look of moderate to severe upper facial lines (frown lines, forehead lines, and crow's feet) in adults for a short period of time (temporary).
  • that is injected into glands that make saliva and is used to treat long-lasting (chronic) drooling (sialorrhea) in adults and in children 2 years of age and older.
  • that is injected into muscles and used to:
    • treat increased muscle stiffness in the arm because of upper limb spasticity in adults.
    • treat increased muscle stiffness in the arm in children 2 to 17 years of age with upper limb spasticity, excluding spasticity caused by cerebral palsy.
    • treat the abnormal head position and neck pain with cervical dystonia (CD) in adults.
    • treat abnormal spasm of the eyelids (blepharospasm) in adults.

It is not known if XEOMIN is safe and effective in children younger than:

  • 2 years of age for the treatment of chronic sialorrhea.
  • 2 years of age for the treatment of upper limb spasticity.
  • 18 years of age for the treatment of glabellar frown lines, cervical dystonia or blepharospasm.

Do not take XEOMIN if you: are allergic to XEOMIN or any of the ingredients in XEOMIN (botulinum toxin type A, human albumin and sucrose), had an allergic reaction to any other botulinum toxin product or have a skin infection at the planned injection site.

Before receiving XEOMIN, tell your doctor about all of your medical conditions, including if you:

  • have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig's disease], myasthenia gravis or Lambert-Eaton syndrome).
  • have had any side effect from any other botulinum toxin in the past.
  • have a breathing problem, such as asthma or emphysema.
  • have a history of swallowing problems or inhaling food or fluid into your lungs (aspiration).
  • have bleeding problems.
  • have drooping eyelids.
  • have plans to have surgery.
  • have had eye surgery.
  • have had surgery on your face.
  • are pregnant or plan to become pregnant. It is not known if XEOMIN can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if XEOMIN passes into breast milk.

Using XEOMIN with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received XEOMIN in the past. Especially tell your doctor if you:

  • have received any other botulinum toxin product in the last four months.
  • have received injections of botulinum toxin in the past. Be sure your doctor knows exactly which product you received. The dose of XEOMIN may be different from other botulinum toxin products that you have received.
  • have recently received an antibiotic by injection or inhalation.
  • take muscle relaxants.
  • take an allergy or cold medicine.
  • take a sleep medicine.

What should I avoid while taking XEOMIN?

XEOMIN may cause loss of strength or general muscle weakness, blurred vision, or drooping eyelids within hours to weeks of taking XEOMIN. If this happens, do not drive a car, operate machinery, or do other dangerous activities.

What are the possible Side Effects of XEOMIN?

XEOMIN can cause serious side effects including:

  • Injury to the cornea (the clear front surface of the eye) in people treated for blepharospasm. People who receive XEOMIN to treat spasm of the eyelid may have reduced blinking that can cause a sore on their cornea or other problems of the cornea. Call your healthcare provider or get medical care right away if you have eye pain or irritation after treatment with XEOMIN.
  • XEOMIN may cause other serious side effects including allergic reactions. Symptoms of an allergic reaction to XEOMIN may include: itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing or trouble breathing, or if you get dizzy or faint.

The most common side effects of XEOMIN in adults with upper facial lines include:

  • injection site bruising

The most common side effects of XEOMIN in adults with chronic sialorrhea include:

  • needing to have a tooth pulled (extracted)
  • diarrhea
  • dry mouth
  • high blood pressure

The most common side effects of XEOMIN in children 2 to 17 years of age with chronic sialorrhea include:

  • bronchitis
  • headache
  • nausea
  • vomiting

The most common side effects of XEOMIN in adults with upper limb spasticity include:

  • seizure
  • dry mouth
  • nasal congestion, sore throat and runny nose
  • upper respiratory infection

The most common side effects of XEOMIN in children 2 to 17 years of age with upper limb spasticity include:

  • nasal congestion, sore throat and runny nose
  • bronchitis

The most common side effects of XEOMIN in adults with cervical dystonia include:

  • difficulty swallowing
  • pain at the injection site
  • neck pain
  • muscle and bone pain
  • muscle weakness

The most common side effects of XEOMIN in adults with blepharospasm include:

  • drooping of the eyelid
  • vision problems
  • dry eye
  • dry mouth

These are not all the possible side effects of XEOMIN.

Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Full Prescribing Information and Medication Guide.

XEOMIN® (incobotulinumtoxinA) IMPORTANT CONSUMER SAFETY INFORMATION
What is the most important information I should know about XEOMIN?
  • XEOMIN may cause serious side effects that can be life threatening. Problems swallowing, speaking, or breathing can happen within hours to weeks after an injection of XEOMIN if the muscles that you use to breathe and swallow become weak. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with XEOMIN.
    • People with certain breathing problems may need to use muscles in their neck to help them breathe and may be at greater risk for serious breathing problems with XEOMIN.
    • Swallowing problems may last for several months, and during that time you may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN have the highest risk of getting these problems.
  • Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.

These symptoms can happen hours to weeks after you receive an injection of XEOMIN. These problems could make it unsafe for you to drive a car or do other dangerous activities.


What is XEOMIN?

XEOMIN is a prescription medicine:

  • that is injected into glands that make saliva and is used to treat long-lasting (chronic) drooling (sialorrhea) in adults and in children 2 years of age or older.
  • that is injected into muscles and used to:
    • treat increased muscle stiffness in the arm because of upper limb spasticity in adults.
    • treat increased muscle stiffness in the arm in children 2 to 17 years of age with upper limb spasticity, excluding spasticity caused by cerebral palsy.
    • treat the abnormal head position and neck pain with cervical dystonia (CD) in adults.
    • treat abnormal spasm of the eyelids (blepharospasm) in adults.

It is not known if XEOMIN is safe and effective in children younger than:

  • 2 years of age for the treatment of chronic sialorrhea
  • 2 years of age for the treatment of upper limb spasticity
  • 18 years of age for the treatment of cervical dystonia or blepharospasm

Do not take XEOMIN if you: are allergic to XEOMIN or any of the ingredients in XEOMIN (botulinum toxin type A, human albumin, and sucrose), had an allergic reaction to any other botulinum toxin product, or have a skin infection at the planned injection site.

Before receiving XEOMIN, tell your doctor about all of your medical conditions, including if you:

  • have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig's disease], myasthenia gravis or Lambert-Eaton syndrome)
  • have had any side effect from any other botulinum toxin in the past
  • have a breathing problem, such as asthma or emphysema
  • have a history of swallowing problems or inhaling food or fluid into your lungs (aspiration)
  • have drooping eyelids
  • have had eye surgery
  • have had surgery on your face
  • are pregnant or plan to become pregnant. It is not known if XEOMIN can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if XEOMIN passes into breast milk.

Using XEOMIN with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received XEOMIN in the past.

Especially tell your doctor if you:

  • have received any other botulinum toxin product in the last four months
  • have received injections of botulinum toxin in the past. Be sure your doctor knows exactly which product you received. The dose of XEOMIN may be different from other botulinum toxin products that you have received.
  • have recently received an antibiotic by injection or inhalation
  • take muscle relaxants
  • take an allergy or cold medicine
  • take a sleep medicine
What should I avoid while taking XEOMIN?

XEOMIN may cause loss of strength or general muscle weakness, blurred vision, or drooping eyelids within hours to weeks of taking XEOMIN. If this happens, do not drive a car, operate machinery, or do other dangerous activities.


What are the possible Side Effects of XEOMIN?

XEOMIN can cause serious side effects including:

  • Injury to the cornea (the clear front surface of the eye) in people treated for blepharospasm. People who receive XEOMIN to treat spasm of the eyelid may have reduced blinking that can cause a sore on their cornea or other problems of the cornea. Call your healthcare provider or get medical care right away if you have eye pain or irritation after treatment with XEOMIN.
  • XEOMIN may cause other serious side effects including allergic reactions. Symptoms of an allergic reaction to XEOMIN may include: itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing or trouble breathing, or if you get dizzy or faint.

The most common side effects of XEOMIN in adults with chronic sialorrhea include:

  • needing to have a tooth pulled (extracted)
  • diarrhea
  • dry mouth
  • high blood pressure

The most common side effects of XEOMIN in children 2 to 17 years of age with chronic sialorrhea include:

  • bronchitis
  • headache
  • nausea
  • vomiting

The most common side effects of XEOMIN in adults with upper limb spasticity include:

  • seizure
  • dry mouth
  • nasal congestion, sore throat and runny nose
  • upper respiratory infection

The most common side effects of XEOMIN in children 2 to 17 years of age with upper limb spasticity include:

  • nasal congestion, sore throat and runny nose
  • bronchitis

The most common side effects of XEOMIN in adults with cervical dystonia include:

  • difficulty swallowing
  • muscle weakness
  • neck pain
  • muscle and bone pain
  • pain at the injection site

The most common side effects of XEOMIN in adults with blepharospasm include:

  • drooping of the eyelid
  • dry eye
  • vision problems
  • dry mouth

These are not all the possible side effects of XEOMIN.

  • Call your doctor for medical advice about side effects.
  • You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

The risk information provided here is not comprehensive. To learn more: